Plectranthus

[m.speciosa]

Plectranthus: a review of ethnobotanical uses
Journal of ethnopharmacology, 2006



https://www.academia.edu/12256431/Plect ... nical_uses

[m.speciosa]

The leaves are used as a snuff - a habit that can become addictive

In der Kultur sind sie sehr einfach. Auch im Winter.

Es gibt massenhaft interessante Arten.


lamiaceae
plectranthus

[syzygy]

Ja, ist wirklich eine interessante Gattung!

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Bioactivities of decoctions from Plectranthus species related to their traditional use on the treatment of digestive problems and alcohol intoxication.

ETHNOPHARMACOLOGICAL RELEVANCE: Decoctions of Plectranthus species are traditionally ingested after large meals for treatment of food digestion and alcohol abuse.

AIM OF THE STUDY: This study aims at associating the digestion-related ethno-uses of Plectranthus species decoctions to molecular mechanism that might explain them: easing digestion (AChE inhibition) and treating hangover (ADH inhibition)

MATERIAL AND METHODS: Decoctions from Plectranthus species were analysed for their alcohol dehydrogenase (ADH) inhibition and acetylcholinesterase (AChE) inhibition, related with alcohol metabolism and intestinal motility, respectively. Identification of the active components was carried out by LC-MS/MS and the docking studies were performed with AChE and the bioactive molecules detected.

RESULTS: All decoctions inhibited ADH activity. This inhibition was correlated with their rosmarinic acid (RA) content, which showed an IC50 value of 19 μg/mL, similar to the reference inhibitor CuCl2. The presence of RA also leads to most decoctions showing AChE inhibiting capacity. P. zuluensis decoction with an IC50 of 80 μg/mL presented also medioresinol, an even better inhibitor of AChE, as indicated by molecular docking studies. Furthermore, all decoctions tested showed no toxicity towards two human cell lines, and a high capacity to quench free radicals (DPPH), which also play a helpful in the digestive process, related with their RA content.


CONCLUSIONS: All activities presented by the RA-rich Plectranthus decoctions support their use in treating digestion disorders and P. barbatus could explain its use also for alleviating hangover symptoms. Medioresinol, which is present in P. zuluensis, exhibited a significant AChE inhibition and may provide, in the future, a new lead for bioactive compounds.

Q: https://www.ncbi.nlm.nih.gov/pubmed/29626671

[syzygy]

Plectranthus: A plant for the future?
https://www.researchgate.net/publicatio ... the_future
The genus Plectranthus (Lamiaceae) is a significant, prolific and extensively used genus in southern Africa. It plays a dominant role in both horticulture and traditional medicine. Some 12 species are documented for their use in treating ailments by various indigenous peoples of southern Africa. It is a firm favourite in gardens and Plectranthus has been bred to further utilise the remarkable diversity of indigenous South African wildflowers with amenity horticultural potential. Although previously subjected to both horticultural (Van Jaarsveld, 2006) and ethnobotanical (Lukhoba et al., 2006) review, Plectranthus is a genus with economic potential in various sectors, and this article aims to review this potential of southern African species.

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Plectranthus: a review of ethnobotanical uses
Journal of ethnopharmacology, 2006



https://www.academia.edu/12256431/Plect ... nical_uses

Oder hier ohne den ganzen Accounts zum DL:
https://www.researchgate.net/publicatio ... nical_uses
Plectranthus is a large and widespread genus with a diversity of ethnobotanical uses. The genus is plagued with numerous nomenclatural disharmonies that make it difficult to collate accurate data on the uses. The aim of this review is to gather together all ethnobotanical information on Plectranthus and to map the data onto the most up-to-date phylogenetic classification in order to see if there are similar uses among related species and hence provide a framework for the prediction and exploration of new uses of species.

[syzygy]

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Zu flauschig die Kleine

[Zebra]

Sehen echt toll aus die Pflänzchen

[m.speciosa]

https://phytokeys.pensoft.net/articles.php?id=34988

Hier schonmak ein teil zur Nomenklatur